| Autor: |
Gültaç Evren, Mustafa Bak, Erkin Serdaroglu, Burak Durmaz, Ferda Özkınay |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Journal of Behçet Uz Children's Hospital, Vol 11, Iss 2, Pp 133-138 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2822-4469 |
| DOI: |
10.5222/buchd.2021.57767 |
| Popis: |
Objective: This study aims to investigate the relationship between peritonitis attacks and mannose-binding lectin (MBL) gene polymorphism in patients undergoing peritoneal dialysis. Method: Codon 54 polymorphism found in exon 1 of the MBL gene was investigated by polymerase chain reaction-restriction fragment length polymorphism method in 45 patients with chronic renal failure undergoing peritoneal dialysis. Results: The frequency of the mutant B allele was not significantly higher in the patient group (4.4%) than the control group (2.1%). The AB genotype was found at a rate of 15.6% and 34% in the patient group and healthy control group, respectively. The AA genotype was found in 80% of children who underwent peritoneal dialysis and 63.8% of the healthy control group. Conclusion: In our study, no relationship was found between peritonitis attacks and MBL gene polymorphism in patients undergoing peritoneal dialysis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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