Noninvasive method to assess the electrical brain activity from rats

Autor: Rosana Ferrari, Aldo Ivan Cespedes Arce, Mariza Pires de Melo, Ernane Jose Xavier Costa
Jazyk: English<br />Portuguese
Rok vydání: 2013
Předmět:
Zdroj: Ciência Rural, Vol 43, Iss 10, Pp 1838-1842 (2013)
Druh dokumentu: article
ISSN: 1678-4596
Popis: This research presents a noninvasive method for the acquisition of brain electrical signal in rat. Was used an electroencephalography (EEG) system developed for bovine and adapted to rats. The bipolar electrode system (needle electrodes) was glued on the surface of the head of the animal without surgical procedures and the other electrode was glued to the tail, as ground. The EEG activity was sampled at 120Hz for an hour. The accuracy and precision of the EEG measurement was performed using Fourier analysis and signal energy. For this, the digital signal was divided into sections successive of 3 seconds and was decomposed into four frequency bands: delta (0.3 to 4Hz), theta (4-8Hz), alpha (8-12Hz) and beta (12-30Hz) and energy (µV²) of the series of time filtered were calculated. The method allowed the acquisition of non-invasive electrical brain signals in conscious rats and their frequency patterns were in agreement with previous studies that used surgical procedures to acquire EEG in rats. This system showed accuracy and precision and will allow further studies on behavior and to investigate the action of drugs on the central nervous system in rats without surgical procedures.
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