| Autor: |
Guang-Ran Yang, Ming-Xia Yuan, Gang Wan, Xue-Lian Zhang, Han-Jing Fu, Shen-Yuan Yuan, Liang-Xiang Zhu, Rong-Rong Xie, Jian-Dong Zhang, Yu-Ling Li, Yan-Hua Sun, Qin-Fang Dai, Da-Yong Gao, Xue-Li Cui, Jian-Qin Gao, Zi-Ming Wang, Ying-Jun Chen, Yong-Jin Li, Dong-Ming Hu, Juan Gao, Ying Gao, Jie Miao, Yu-Jie Chen, Rury. R. Holman |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-021-88927-9 |
| Popis: |
Abstract Obesity increases the risk of developing cardiovascular disease and other metabolic diseases. We intended to compare three different anthropometric indicators of obesity, in predicting the incidence of cardiovascular events in Chinese type 2 diabetes. Beijing Community Diabetes Study was a prospective multi-center study conducted in Beijing community health centers. Type 2 diabetes patients from fourteen community health centers were enrolled at baseline. The primary endpoint was cardiovascular events. The upper quartile of neck circumference (NC) was set as greater NC. A total of 3299 diabetes patients were enrolled. In which, 941 (28.52%) had cardiovascular disease at baseline. Logistic analysis showed that central obesity (waist circumference (WC) above 90 cm in men and 85 cm in women) and greater NC were all related to baseline cardiovascular disease (adjusted OR = 1.49, and 1.55). After 10-year follow-up, 340 (10.31%) had cardiovascular events. Compared with patients without cardiovascular events, those having cardiovascular events had higher BMI, larger WC and NC. Cox regression analysis showed that greater WC and NC were all associated with the occurrence of cardiovascular events (adjusted HR = 1.41, and 1.38). A higher NC and WC might increase the risk of cardiovascular events by about 40% in type 2 diabetes patients in Beijing communities. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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