Autor: |
Tsai-Jung Lin, Yun-Yi Lee, Bieng-Hsian Tzeng, Shih-Ping Yang, Cheng-Wen Ho, Dueng-Yuan Hueng, Jia-Ming Chang, Kun-Lun Huang, Fu-Gong Lin, Ann Chen, Yeukuang Hwu, Shuk-Man Ka |
Jazyk: |
angličtina |
Rok vydání: |
2014 |
Předmět: |
|
Zdroj: |
Journal of Medical Sciences, Vol 34, Iss 2, Pp 56-61 (2014) |
Druh dokumentu: |
article |
ISSN: |
1011-4564 |
DOI: |
10.4103/1011-4564.131888 |
Popis: |
Background: Antroquinonol (Antroq) is an active component of Antrodia camphorate. The present study was to validate the preventive effects of Antroq in an atherosclerosis model. Materials and Methods: We examined Antroq inhibitory effect on rat aortic smooth muscle cell proliferation and migration and evaluated its effect on neointima formation and inflammation in mouse carotid artery ligation (CAL). Results: Our data show that Antroq [1] inhibited the proliferation (Antroq [3.0 μg/ml] + PDGF 41.7 ± 7.3%, vehicle + PDGF 134.5 ± 7.3%) (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|