| Autor: |
H. Y. Chow, B. Dong, C. A. Valencia, C. T. Zeng, J. N. Koch, T. Y. Prudnikova, J. Chernoff |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-018-05935-6 |
| Popis: |
Group I Paks, like Pak1, are required for the activation of several key oncogenic signaling pathways. Here the authors study an inducible peptide mimicking the auto-inhibitory domain of Pak1 and show promising anti-tumor effects in a mouse model of colorectal cancer. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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