Blood pressure and lipid profiles in adolescents with hypertensive parents
| Autor: | Julia Fitriany, Rafita Ramayati, Supriatmo Supriatmo, Rusdidjas Rusdidjas, Oke Rina, Rosmayanti Siregar |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Paediatrica Indonesiana, Vol 55, Iss 6, Pp 333-8 (2016) |
| Druh dokumentu: | article |
| ISSN: | 0030-9311 2338-476X |
| DOI: | 10.14238/pi55.6.2015.333-8 |
| Popis: | Background Adolescent hypertension is a significant health problem of increasing prevalence and causes high morbidity and mortality. It is found primarily in young males, with a familial history of hypertension and/or cardiovascular disease. Examination of lipid profiles has been used to detect the risk of hypertension in adolescents. Objective To compare blood pressure and lipid profiles in adolescents with and without a parental history of hypertension. Methods This cross-sectional study was conducted from January to February 2012 on students from a senior high school in the Toba Samosir District, North Sumatera. Sixty-eight adolescents were included, aged 15 to 18 years. Group I comprised 34 adolescents with hypertensive parents, and group II comprised 34 adolescents with normotensive parents. Subjects were selected based on questionnaires. Subjects’ blood pressures were measured at rest. Three measurements were made in intervals of 10-15 minutes, then averaged for both systolic and diastolic blood pressures. Lipid profiles were measured using the CardioCheck cholesterol test after subjects had fasted for 12 hours. Results The median systolic blood pressures (SBP) in groups I and II were 110 mmHg (range 93.3-123.3) and 106.7 mmHg (range 96.7-123.3), respectively, (P=0.584). The median diastolic blood pressures (DBP) were 73.3 mmHg (range 66.7-83.3) and 71.7 mmHg (range 63.3-80.0), respectively, (P=0.953). Total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels in group I were significantly higher than those levels in group II [median total cholesterol: 162.0 (range 158-170) vs. 159.0 (range 150-170), respectively; (P=0.001); and mean LDL-C: 103.5 (SD 3.72) vs. 99.1 (SD 4.63), respectively; (P=0.001). Multivariate analysis revealed a correlation of moderate strength between parental history of hypertension and increased LDL-C (P |
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