Heart Failure Etiology in Patients Undergoing Cardiac Resynchronization Therapy: Is It Relevant?
| Autor: | Silvia DEACONU, Alexandru DEACONU, Alina SCARLATESCU, Ioana PETRE, Sebastian ONCIUL, Aura VIJIAC, Amalia PETRE, Gabriela MARASCU, Corneliu IORGULESCU, Andrei Dan RADU, Stefan BOGDAN, Radu VATASESCU, Maria DOROBANTU |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Modern Medicine, Vol 28, Iss 2, Pp 153-159 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1223-0472 2360-2473 |
| DOI: | 10.31689/rmm.2021.28.2.153 |
| Popis: | Background: Cardiac resynchronization therapy (CRT) is an established treatment for heart failure with reduced ejection fraction (HfrEF). Etiology may influence the outcome of patients undergoing CRT. Objective: to evaluate whether etiology (ischemic vs non-ischemic) influences the response to CRT and overall outcome. Methods: Our study included HFrEF patients undergoing CRT between January 2017-November 2019. We assessed right ventricle (RV) and left ventricle (LV) function using transthoracic echocardiography at baseline and one year after CRT. The response to CRT was defined by a decrease of more than 15% of left ventricle systolic volume. Patients were divided in two groups: ischemic and non-ischemic based on personal history. Adverse events (HF related hospitalizations and deaths) were tracked for 33± 12.8 months. Results: 52 patients undergoing CRT were included (64±13.5 years, 55.7% male, 70% non-ischemic etiology) The two groups were similar considering LV systolic baseline parameters and volumes. Ischemic etiology was associated with non-LBBB morphology on ECG (p=0.03), a more severe LV diastolic dysfunction using E/e ratio (p |
| Databáze: | Directory of Open Access Journals |
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