Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space

Autor: O. Akinduro, T. S. Weber, H. Ang, M. L. R. Haltalli, N. Ruivo, D. Duarte, N. M. Rashidi, E. D. Hawkins, K. R. Duffy, C. Lo Celso
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-02376-5
Popis: How leukaemia cells invade the bone marrow by outcompeting haematopoietic cells is still unclear. Here, the authors used detailed cell number measurements in conjunction with a dual pulse labelling method to determine proliferation rates and followed the in vivo dynamics of AML disease progression.
Databáze: Directory of Open Access Journals