| Autor: |
Fiona Mankertz, Rebecca Keßler, Andrea Rau, Christian Seebauer, Silvia Ribback, Alexandra Busemann |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Diseases, Vol 11, Iss 3, p 108 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2079-9721 |
| DOI: |
10.3390/diseases11030108 |
| Popis: |
An aneurysmal fibrous histiocytoma is a rare cutaneous soft-tissue tumour which accounts for approximately 0.06% of all dermatopathologies. Metastasis is exceedingly uncommon, to the point that there have only been eight reported cases in the scientific literature. We present the case of a 25-year-old male with a primary aneurysmal fibrous histiocytoma located in the nuchal region which exhibited rapid growth and abrupt ulceration over a short time span and showed signs of locoregional aggressive infiltration. A subsequent histopathological analysis confirmed the presence of diffuse solid and cystic pulmonary metastases. Further genetic sequencing verified LAMTOR1-PRKCD fusion. This case report seeks to review the existing literature on aneurysmal fibrous histiocytoma, discuss the challenges of differential diagnosis and propose standardised diagnostic criteria. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
