Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Autor: Nadine Mestre-Francés, Simon Nicot, Sylvie Rouland, Anne-Gaëlle Biacabe, Isabelle Quadrio, Armand Perret-Liaudet, Thierry Baron, Jean-Michel Verdier
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 18, Iss 1, Pp 142-145 (2012)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid1801.111092
Popis: We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.
Databáze: Directory of Open Access Journals
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