| Autor: |
Hung-Da Chou, Cheng-Hsiu Wu, Wei-Yu Chiang, Nan-Ni Chen, Yih-Shiou Hwang, Kuan-Jen Chen, Chien-Hsiung Lai, Pei-Chang Wu, Yi-Hao Chen, Ling Yeung, Shih-Chieh Shao, Chi-Chun Lai, Wei-Chi Wu |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-022-07604-7 |
| Popis: |
Abstract In this retrospective, multicenter study, we determined the predictive value of imaging biomarkers in diabetic macular edema (DME) outcomes following dexamethasone (DEX) implant(s). Sixty-seven eyes of 47 patients’ best-corrected visual acuity (BCVA) and central foveal thickness (CFT) on optical coherence tomography (OCT) before and after intravitreal DEX implants were evaluated. Baseline imaging biomarkers were graded using fundus photography and OCT, and the predictive value of biomarkers for significant treatment effects at six months was analyzed. Six months after 2.0 ± 0.8 (mean ± SD) DEX implants, 35 (52%) and 16 (24%) eyes had CFT reduction ≥ 10% from baseline and decreased to |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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