Hereditary mechanisms in the development of sclerotic degenerative disorders of aortic valve

Autor:	N. N. Parfenova, S. I. Khasanova, L. B. Mitrofanova, E. V. Dubova, E. V. Zemtsovsky
Jazyk:	ruština
Rok vydání:	2013
Předmět:	hereditary connective tissue disorders marfanoid habitus calcific aortic stenosis Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Российский кардиологический журнал, Vol 0, Iss 1, Pp 50-53 (2013)
Druh dokumentu:	article
ISSN:	1560-4071 2618-7620
DOI:	10.15829/1560-4071-2013-1-50-53
Popis:	Aim. To investigate the role of hereditary mechanisms in the development of sclerotic degenerative disorders of aortic valve. Material and methods. Clinical, phenotypical, and echocardiographic examination was performed in 180 middle-aged and elderly people (mean age 63,8±9 years; 102 men, 78 women), including 86 patients with calcific aortic stenosis (55 after aortic valve surgery) and 61 controls. The diagnostic criteria of the National Guidelines on hereditary connective tissue disorders (2009) were used. The valve biopsy samples were examined using histological, morphological, and immunohistochemical (TGF-
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/390dcaa5473d4bb590489ddcea5e4111 Zobrazit plný text záznamu View record in DOAJ