Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi

Autor: Javier Emperador-Melero, Vincent Huson, Jan van Weering, Christian Bollmann, Gabriele Fischer von Mollard, Ruud F. Toonen, Matthijs Verhage
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-05699-z
Popis: Vti1a and Vti1b are SNARE proteins implicated in regulated secretion. Here the authors show that Vti1a and Vti1b control protein sorting at the Golgi, and targeting to the axon, and thereby indirectly control regulated secretion at the synapse.
Databáze: Directory of Open Access Journals