| Autor: |
Annette Löffler, Florian Beier, Robin Bekrater-Bodmann, Lucrezia Hausner, Simon Desch, Stefano Silvoni, Dieter Kleinböhl, Martin Löffler, Frauke Nees, Lutz Frölich, Herta Flor |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
EBioMedicine, Vol 99, Iss , Pp 104896- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2352-3964 |
| DOI: |
10.1016/j.ebiom.2023.104896 |
| Popis: |
Summary: Background: Sensory impairment has been related to age-associated cognitive decline. While these associations were investigated primarily in the auditory and visual domain, other senses such as touch have rarely been studied. Thus, it remains open whether these results are specific for particular sensory domains, or rather point to a fundamental role of sensory deficits in cognitive decline. Methods: Data from 31 participants with mild cognitive impairment (MCI), 46 participants with frailty, and 23 non-clinical control participants (NCCs) were included. We assessed sensory function using visual acuity and contrast sensitivity, hearing threshold, and mechanical detection threshold. Cognitive function in participants with MCI was assessed using associative memory performance. Group differences on sensory thresholds were tested using analyses of covariance with age, sex, and years of education as covariates. Associations between measures within participants with MCI were evaluated using Spearman correlations. Findings: We found a significant difference in mechanical detection threshold between the groups (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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