| Autor: |
Qi Wang, Hong Zhao, Li-Gai Liu, Yan-Bin Wang, Ting Zhang, Ming-Hui Li, Yan-Li Xu, Gui-Ju Gao, Hao-Feng Xiong, Ying Fan, Ying Cao, Rui Ding, Jing-Jing Wang, Cheng Cheng, Wen Xie |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Military Medical Research, Vol 7, Iss 1, Pp 1-8 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2054-9369 |
| DOI: |
10.1186/s40779-020-00256-6 |
| Popis: |
Abstract Background Recent studies reported that patients with coronavirus disease-2019 (COVID-19) might have liver injury. However, few data on the combined analysis and change patterns of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBil) have been shown. Methods This is a single-center retrospective study. A total of 105 adult patients hospitalized for confirmed COVID-19 in Beijing Ditan Hospital between January 12, and March 17, 2020 were included, and divided into mild group (n = 79) and severe group(n = 26). We compared liver functional test results between the two groups. Category of ALT change during the disease course was also examined. Results 56.2% (59/105) of the patients had unnormal ALT, AST, or total TBil throughout the course of the disease, but in 91.4% (96/105) cases the level of ALT, AST or TBil ≤3 fold of the upper limit of normal reference range (ULN). The overall distribution of ALT, AST, and TBil were all significantly difference between mild and severe group (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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