A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review

Autor: Asma Salameh Albtoosh, Moayad Shaf'ei, Sa'ed Al Hayek, Lara Ibrahim Ramdan, Nisreen Abu Shahin, Mohammad Alzyoud, Randa Farah
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Clinical Case Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2050-0904
DOI: 10.1002/ccr3.7540
Popis: Abstract Mucormycosis is an opportunistic fungal infection that usually affects patients with diabetes mellitus or immunosuppression. The fungus invades the nearby blood vessels leading to thrombosis and necrosis of the organs involved. Although Mucorales can invade any organ in the body, the gastrointestinal system is an uncommon site for infection. Mucormycosis is a fatal infection, and prompt intervention is required to ensure survival. In this report, we present a case of a 46‐year‐old man with history of valve replacement surgery on warfarin, who admitted with abdominal pain and life‐threatening gastrointestinal bleeding. Esophagogastroduodenoscopy revealed an active gastric ulcer bleeding, and the diagnosis of mucormycosis infection was confirmed with direct microscopy and histopathological evaluation from a tissue biopsy. Typically, antifungal therapy alone is inadequate to control mucormycosis infection and surgical intervention is often required. Our patient was successfully treated using antifungal therapy alone. This report presents a rare case of gastrointestinal mucormycosis in setting of valve replacement and was successfully treated with antifungal therapy.
Databáze: Directory of Open Access Journals
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