Familial unilateral Brown syndrome
| Autor: | Kenawy Nihal, Pilz Daniela, Watts Patrick |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: | |
| Zdroj: | Indian Journal of Ophthalmology, Vol 56, Iss 5, Pp 430-434 (2008) |
| Druh dokumentu: | article |
| ISSN: | 0301-4738 1998-3689 |
| Popis: | We present a two-generation family with Brown syndrome. The proband was a six and a half-year-old female who presented with a history of failure of dextro-elevation of her left eye. A full ophthalmic evaluation was consistent with a left Brown syndrome. Family history revealed that her mother was operated on as a child for left Brown syndrome and examination of her four and a half-year-old sibling showed similar affection in the left eye. Autosomal dominant inheritance has been postulated in this condition. To our knowledge this is the first report of three members of a two-generation family with left-sided Brown syndrome. Genetic counseling of Brown syndrome cases is advised; nevertheless, identification of the responsible gene should shed more light on its genetics. |
| Databáze: | Directory of Open Access Journals |
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