LSVT-BIG Improves UPDRS III Scores at 4 Weeks in Parkinson’s Disease Patients with Wearing Off: A Prospective, Open-Label Study
| Autor: | Tatsuya Ueno, Megumi Sasaki, Haruo Nishijima, Yukihisa Funamizu, Tomoya Kon, Rie Haga, Akira Arai, Chieko Suzuki, Jin-ichi Nunomura, Masayuki Baba, Masahiko Tomiyama |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Parkinson's Disease, Vol 2017 (2017) |
| Druh dokumentu: | article |
| ISSN: | 2090-8083 2042-0080 |
| DOI: | 10.1155/2017/8130140 |
| Popis: | The efficacy of LSVT-BIG for advanced Parkinson’s disease (PD) patients with wearing off remains to be determined. Therefore, we evaluated whether LSVT-BIG improves motor disability in eight PD patients with wearing off. Unified Parkinson’s Disease Rating Scale (UPDRS) scores, daily off time, and mobility assessments were evaluated during the “on” time before and after the LSVT-BIG course. LSVT-BIG significantly improved UPDRS III scores at 4 weeks and UPDRS II scores in the “off” state at 12 weeks, with no changes in the other measures. The findings suggest that LSVT-BIG may be an effective therapy for advanced PD patients with wearing off. |
| Databáze: | Directory of Open Access Journals |
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