A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection

Autor: Shancheng Si, Wei Su, Lei Wang, Yicong Ji, Anming Chen, Yuntao Hu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Ophthalmology, Vol 23, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 1471-2415
DOI: 10.1186/s12886-023-02992-4
Popis: Abstract Purpose To observe long-term prognosis of anterior segment ischemia (ASI) following hyaluronic acid (HA) injection, propose a severity grading system for ASI and a predictive model for phthisis bulbi (PB) based on long-term secretion dysfunction of ciliary process. Methods This is a retrospective case–control study. All enrolled 20 patients were divided into two groups and followed for at least 6 months to observe the formation and transformation characteristics of ASI and long-term prognosis based on the degrees of ciliary function damage. Results The severity of ASI following HA injection could be subdivided into 4 grades according to the degrees of ciliary function damage, comprising ASI grades 0, 1, 2 and 3. In 20 patients, ophthalmoplegia at 1-month follow-up, ASI within 1 month, ASI at 1-month follow-up, hypotony within 6 months were all significantly more common in study group than in control group (60% vs. 0%, P = 0.011; 100% vs. 20%, P = 0.001; 100% vs. 0%, P
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