Clinical markers in heart failure: a narrative review

Autor: Nismat Javed, Markos El-Far, Timothy J. Vittorio
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of International Medical Research, Vol 52 (2024)
Druh dokumentu: article
ISSN: 1473-2300
03000605
DOI: 10.1177/03000605241254330
Popis: Heart failure is a complex clinical syndrome that is one of the causes of high mortality worldwide. Additionally, healthcare systems around the world are also being burdened by the aging population and subsequently, increasing estimates of patients with heart failure. As a result, it is crucial to determine novel ways to reduce the healthcare costs, rate of hospitalizations and mortality. In this regard, clinical biomarkers play a very important role in stratifying risk, determining prognosis or diagnosis and monitoring patient responses to therapy. This narrative review discusses the wide spectrum of clinical biomarkers, novel inventions of new techniques, their advantages and limitations as well as applications. As heart failure rates increase, cost-effective diagnostic tools such as B-type natriuretic peptide and N-terminal pro b-type natriuretic peptide are crucial, with emerging markers like neprilysin and cardiac imaging showing promise, though larger studies are needed to confirm their effectiveness compared with traditional markers.
Databáze: Directory of Open Access Journals