Heterogeneity in Breast Cancer and the Problem of Relevance of Findings
| Autor: | M. Aubele, M. Werner |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1999 |
| Předmět: | |
| Zdroj: | Analytical Cellular Pathology, Vol 19, Iss 2, Pp 53-58 (1999) |
| Druh dokumentu: | article |
| ISSN: | 0921-8912 1878-3651 |
| DOI: | 10.1155/1999/960923 |
| Popis: | Many attempts are made to identify critical genetic events responsible for the development and progression of breast cancer. There is increasing evidence that breast cancer is a heterogeneous disease, both, phenotypically as well as with respect to its molecular biologically. It is, therefore, extremely difficult to establish a diagnostically and prognostically relevant tumourigenesis model. Emerging new techniques such as microarrays, will provide us with a wealth of additional data over the next years. The precise sampling of tumour material in clearly defined histopathological lesions will be a prerequisite for the assignment of specific genetic alterations to defined stages of breast disease. |
| Databáze: | Directory of Open Access Journals |
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