| Autor: |
Della Makower, Jiyue Qin, Juan Lin, Xiaonan Xue, Joseph A. Sparano |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
npj Breast Cancer, Vol 8, Iss 1, Pp 1-7 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2374-4677 |
| DOI: |
10.1038/s41523-021-00368-9 |
| Popis: |
Abstract The 21-gene recurrence score (RS) is prognostic for recurrence and predictive of chemotherapy benefit in early estrogen receptor-positive (ER +) HER2-negative (HER2-) breast cancer (BCA). We evaluated clinicopathologic characteristics, RS and chemotherapy benefit in invasive ductal carcinoma (IDC), invasive lobular carcinoma (ILC), and carcinomas of mixed histologies (ductal + lobular (DLC), ductal + other (DOC), lobular + other (LOC)). Women diagnosed between 1/1/2010 and 1/1/2014 with ER + HER2- BCA, measuring 26. ILC was associated with larger size, and least likely to be high grade (p 26. IDC patients (pts) were more likely to receive chemotherapy than pts with other histologies (p 26 cannot be excluded. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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