Combination of dihydropyridine and non-dihydropyridine calcium antagonists in patients with arterial hypertension and coronary heart disease: efficacy and safety
Autor: | B. G. Iskanderov, T. V. Lokhina, L. F. Burmistrova, L. V. Kazantseva, S. R. Bogdanova |
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Jazyk: | ruština |
Rok vydání: | 2005 |
Předmět: | |
Zdroj: | Кардиоваскулярная терапия и профилактика, Vol 4, Iss 6, ч.II, Pp 38-43 (2005) |
Druh dokumentu: | article |
ISSN: | 1728-8800 2619-0125 |
Popis: | Aim. To study antihypertensive and anti-ischemic effects on structural and functional heart status, and assess treatment safety for combination of dihydropyridine and non-dihydropyridine calcium antagonists (CA). Material and methods. The authors examined 31 patients with Stage II-III, level II arterial hypertension (AH) (Society of Cardiology of the Russian Federation, 2001), and coronary heart disease (CHD), effort angina, Functional Class (FC) II-III. Twenty-four-hour electrocardiography (ECG) and blood pressure (BP) monitoring, Doppler echocardiography (EchoCG) were performed. Combined therapy with amlodipine and verapamil retard lasted for 24 weeks. Results. During the treatment, in 77.4% of the patients, complete antihypertensive effect (BP |
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