Combination of dihydropyridine and non-dihydropyridine calcium antagonists in patients with arterial hypertension and coronary heart disease: efficacy and safety

Autor: B. G. Iskanderov, T. V. Lokhina, L. F. Burmistrova, L. V. Kazantseva, S. R. Bogdanova
Jazyk: ruština
Rok vydání: 2005
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 4, Iss 6, ч.II, Pp 38-43 (2005)
Druh dokumentu: article
ISSN: 1728-8800
2619-0125
Popis: Aim. To study antihypertensive and anti-ischemic effects on structural and functional heart status, and assess treatment safety for combination of dihydropyridine and non-dihydropyridine calcium antagonists (CA). Material and methods. The authors examined 31 patients with Stage II-III, level II arterial hypertension (AH) (Society of Cardiology of the Russian Federation, 2001), and coronary heart disease (CHD), effort angina, Functional Class (FC) II-III. Twenty-four-hour electrocardiography (ECG) and blood pressure (BP) monitoring, Doppler echocardiography (EchoCG) were performed. Combined therapy with amlodipine and verapamil retard lasted for 24 weeks. Results. During the treatment, in 77.4% of the patients, complete antihypertensive effect (BP
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