Long-term efficacy and safety of adjunctive perampanel in pediatric patients aged 4–19 years with epilepsy: a real-world study

Autor:	Song Ee Youn, Hoon-Chul Kang, Joon Soo Lee, Heung Dong Kim, Se Hee Kim
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Medicine Science
Zdroj:	Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-023-40594-8
Popis:	Abstract This study determined the 24-month outcomes of perampanel treatment in children and adolescents with epilepsy. The percentage of ≥ 50% responders was 47.3% (139/294) at 12 months and 49.0% (144/294) at 24 months. A 100% reduction in seizures for more than 12 months was observed in 12.2% (36/294). Discontinuation occurred in 39.8% (117/294). The most common reason for discontinuation was adverse events (29.1%, 34/117). Baseline seizure frequency was higher in children aged
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/38574e96024141f292977da9741a4de3 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.