Pseudothrombocytopenia: a case of platelet satellitism and phagocytosis by neutrophils

Autor:	Sara M. Sousa, Teresa M. Sousa, Cristina F. Silva, Carlos C. Mendes
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	pseudothrombocytopenia platelet satellitism platelet phagocytosis neutrophils edta-dependent autoantibodies Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Platelets, Vol 31, Iss 4, Pp 541-543 (2020)
Druh dokumentu:	article
ISSN:	0953-7104 1369-1635 09537104
DOI:	10.1080/09537104.2019.1664733
Popis:	Thrombocytopenia is a clinically important condition that can lead to several problems when not correctly diagnosed. A decrease of platelet counts due to an in vitro phenomenon, Pseudothrombocytopenia, can be misunderstood and unnecessarily treated. The present case study describes a 57-year-old male with a history of pancreas adenocarcinoma and a current Staphylococcus aureus infection without any signs or symptoms that could explain the low levels of platelets obtained after blood analysis. Blood smear evaluation detected both platelet satellitism and phagocytosis by neutrophils. As this sample was anticoagulated with ethylenediaminetetraacetic acid (EDTA), a new blood sample with citrate was analyzed. Platelet count was normal and no morphological abnormalities were detected. This case emphasizes the need for considering not only laboratory results but also the patient clinical information to guarantee the correct diagnosis and the best treatment possible.
Databáze:	Directory of Open Access Journals
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