Direct Switch from Tiotropium to Indacaterol/Glycopyrronium in Chronic Obstructive Pulmonary Disease Patients in Korea
| Autor: | Sang Haak Lee, Chin Kook Rhee, Kwangha Yoo, Jeong Woong Park, Suk Joong Yong, Jusang Kim, Taehoon Lee, Seong Yong Lim, Ji-Hyun Lee, Hye Yun Park, Minyoung Moon, Ki-Suck Jung |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Tuberculosis and Respiratory Diseases, Vol 84, Iss 2, Pp 96-104 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1738-3536 2005-6184 |
| DOI: | 10.4046/trd.2020.0109 |
| Popis: | Background Many chronic obstructive pulmonary disease (COPD) patients receiving monotherapy continue to experience symptoms, exacerbations and poor quality of life. This study aimed to assess the efficacy and safety of direct switch from once-daily tiotropium (TIO) 18 μg to indacaterol/glycopyrronium (IND/GLY) 110/50 μg once daily in COPD patients in Korea. Methods This was a randomized, open-label, parallel group, 12-week trial in mild-to-moderate COPD patients who received TIO 18 μg once daily for ≥12 weeks prior to study initiation. Patients aged ≥40 years, with predicted post-bronchodilator forced expiratory volume in 1 second (FEV1) ≥50%, post-bronchodilator FEV1/forced vital capacity |
| Databáze: | Directory of Open Access Journals |
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