Transfusion-related Acute Lung Injury: Report of Two Cases

Autor: Zuzana Čermáková, M. Kořístka, Š. Blahutová, J. Dvořáčková, R. Brát, I. Valkovský, R. Hrdličková
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Prague Medical Report, Vol 113, Iss 4, Pp 294-298 (2012)
Druh dokumentu: article
ISSN: 23362936
1214-6994
2336-2936
DOI: 10.14712/23362936.2015.13
Popis: Transfusion-related acute lung injury (TRALI) is a severe life-threatening complication of blood transfusion, characterized by acute lung injury developing within 2–6 h of transfusion. However, TRALI is difficult to diagnose, and the initial report or suspicion of TRALI depends on close collaboration between clinical departments and transfusion centres. A total of 17 adverse post-transfusion reactions were reported to the Blood Centre of the University Hospital Ostrava as suspected TRALI between 2005 and 2010. We report two cases of serious TRALI with different pathogenetic mechanisms.
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