Nucleus accumbens functional connectivity and circulating endocannabinoids levels in anorexia nervosa
| Autor: | R. Miranda-Olivos, I. Baenas, A. Pastor, A. Del Pino, E. Codina, I. Sánchez, A. Juaneda-Segui, S. Jimenez-Murcia, R. De La Torre, C. Soriano-Mas, F. Fernandez-Aranda |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | European Psychiatry, Vol 65, Pp S90-S91 (2022) |
| Druh dokumentu: | article |
| ISSN: | 0924-9338 1778-3585 |
| DOI: | 10.1192/j.eurpsy.2022.269 |
| Popis: | Introduction Neuroimaging findings have reported aberrant functional connectivity in brain regions involved reward system in individuals with anorexia nervosa (AN) altering hedonic processing over food. Likewise, endocannabinoids such as Anandamide (AEA) and 2-Arachidonoylglycerol (2-AG) have been involved in rewarding aspects of food intake. Objectives To identify nucleus accumbens (NAcc) functional connectivity with whole-brain comparing between individuals with AN and controls. Furthermore, in a sub-study, to explore the interaction between NAcc functional connectivity and peripheral AEA and 2-AG levels. Methods A total of 60 adult women (18 to 56 years of age) took part in the present study. Twenty-six individuals belonged to the AN group (BMI |
| Databáze: | Directory of Open Access Journals |
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