EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER
| Autor: | V. I. KONONENKO, O. I. KIT, E. F. KOMAROVA, A. Yu. MAKSIMOV, V. V. POZDNYAKOVA, I. A. NOVIKOVA, A. A. DEMIDOVA |
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| Jazyk: | ruština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Кубанский научный медицинский вестник, Vol 1, Iss 1, Pp 64-68 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1608-6228 2541-9544 |
| DOI: | 10.25207/1608-6228-2017-1-64-68 |
| Popis: | While studying the expression of transcription, neoangiogenesis and apoptosis factors in the tumour tissue and oral fluid of 141 patients with oral mucosa cancer T1-3N0-2M0, it was shown that oral mucosa cancer progression combined with postoperative purulent inflammatory complications were associated with a high level of transcription factors, enhanced translocation of hypoxia-inducible factor-1б in the core, high expression of vascular endothelial growth factor and activation of apoptosis in the tumour tissue. The revealed changes in the underlying disease progression have a reasonably greater severity. |
| Databáze: | Directory of Open Access Journals |
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