Generalized morphea/eosinophilic fasciitis overlap after epoxy exposure

Autor: Warren H. Chan, MS, Daniel J. Lewis, BA, Esther J. Kim, BA, Phyu P. Aung, MD, Madeleine Duvic, MD
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: JAAD Case Reports, Vol 4, Iss 2, Pp 175-178 (2018)
Druh dokumentu: article
ISSN: 2352-5126
DOI: 10.1016/j.jdcr.2017.09.006
Popis: Generalized morphea is associated with epoxy resin vapors and is characterized by the development of lesions shortly after exposure. Morphea presenting along with eosinophilic fasciitis (EF), or morphea/EF overlap, is rare and an indicator of poor prognosis and resistance to treatment. Here we present a case of generalized morphea/EF overlap linked to epoxy exposure. Our patient received multiple therapies—ultraviolet A1 phototherapy, prednisone, methotrexate, azathioprine, mycophenolate mofetil, cyclophosphamide, cyclosporine, and rituximab—none of which led to a significant response. The refractory nature of this disease warrants vigilance in its association with epoxy exposure.
Databáze: Directory of Open Access Journals