Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis

Autor: Hong Sheng Quah, Elaine Yiqun Cao, Lisda Suteja, Constance H. Li, Hui Sun Leong, Fui Teen Chong, Shilpi Gupta, Camille Arcinas, John F. Ouyang, Vivian Ang, Teja Celhar, Yunqian Zhao, Hui Chen Tay, Jerry Chan, Takeshi Takahashi, Daniel S. W. Tan, Subhra K. Biswas, Owen J. L. Rackham, N. Gopalakrishna Iyer
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-37379-y
Popis: The molecular mechanisms underlying lymph-node metastasis in head and neck squamous-cell carcinoma remain to be investigated. Here, the authors perform single-cell RNA sequencing of cancer cells and CD8 + T cells and suggest potential mechanisms of immune evasion during early metastasis.
Databáze: Directory of Open Access Journals