Treatment of severe nosocomial infections: doripenem - a new carbapenems antibiotic

Autor:	I N Petukhova, N V Dmitrieva
Jazyk:	ruština
Rok vydání:	2015
Předmět:	pseudomonas aeruginosa acinetobacter baumannii doripenem carbapenems nosocomial infections multi-drug resistant microorganisms acineto-bacter baumannii Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Современная онкология, Vol 17, Iss 2, Pp 67-73 (2015)
Druh dokumentu:	article
ISSN:	1815-1434 1815-1442
Popis:	Doripenem is a new carbapenems antibiotic and takes an important place in the treatment of severe nosocomial infections, as well as in case of infections caused by multi-drug resistant microorganisms; and can be used for the treatment of complicated intraabdominal infection, complicated urinary tract infections (including bacteraemia), nosocomial pneumonia, including ventilator-associated pneumonia. The review presents the data of international studies concerning the determining the susceptibility of microorganisms to doripenem in vitro, including Pseudomonas aeruginosa, Acinetobacter and others, the results of pharmacokinetic and clinical studies with the drug. We discuss the approaches to overcome the microorganism resistance using prolonged infusion of doripenem, as well as antibiotic tolerance and pharmacoeconomic data.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/381ceea7e88b4ed9a7018e35af6e3778 Zobrazit plný text záznamu View record in DOAJ