Autor: |
Kohei Hasegawa, Hiroshi Kurita, Akinari Sakurai, Masaru Mizuki, Teruomi Tsukahara, Tetsuo Nomiyama |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
|
Zdroj: |
BMJ Open, Vol 13, Iss 11 (2023) |
Druh dokumentu: |
article |
ISSN: |
2044-6055 |
DOI: |
10.1136/bmjopen-2023-075527 |
Popis: |
Objectives To investigate the association between the number of teeth and the new onset of pre-diabetes.Design Retrospective cohort study.Setting The National Database of Health Insurance Claims and Specific Health Checkups of Japan, which holds information from both the yearly health check-up programme known as the ‘Specific Health Checkup’ and health insurance claims data.Participants 1 098 371 normoglycaemic subjects who participated in the Specific Health Checkup programme every year from fiscal year (FY) 2015 to FY 2018 and had dental insurance claims data with a diagnosis of periodontal disease during FY 2016.Outcome measures Incidence of pre-diabetes or diabetes observed at the Specific Health Checkup during FY 2018.Results Among the participants, 1 77 908 subjects developed pre-diabetes, and 579 developed diabetes at the check-up during the subsequent follow-up year. Compared with the subjects with 26–28 teeth, those with 20–25, 15–19 or 1–14 teeth were associated with an increased likelihood of developing pre-diabetes or diabetes onset with adjusted ORs of 1.03 (95% CI: 1.02 to 1.05), 1.06 (1.03 to 1.09) and 1.07 (1.04 to 1.11), respectively. No clear modifications were observed for age, sex, body mass index or current smoking.Conclusions Having fewer teeth was associated with a higher incidence of pre-diabetes. Due to the limitations of this study, however, causality remains undetermined. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|