Rasamsonia sp: An emerging infection amongst chronic granulomatous disease patients. A case of disseminated infection by a putatively novel Rasamsonia argillacea species complex involving the heart

Autor: Ahmed Babiker, Nupur Gupta, Connie F.C. Gibas, Nathan P. Wiederhold, Carmita Sanders, James Mele, Hongxin Fan, Alina Iovleva, Ghady Haidar, Carolyn Fernandes
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Medical Mycology Case Reports, Vol 24, Iss , Pp 54-57 (2019)
Druh dokumentu: article
ISSN: 2211-7539
DOI: 10.1016/j.mmcr.2019.04.002
Popis: Chronic granulomatous disease (CGD) is a heterogeneous condition due to defects in NADPH oxidase characterized by granuloma formation and increased susceptibility to invasive infections, in particular moulds. The use of broad-spectrum, mould-active antifungal prophylaxis has improved mortality. However rare resistant moulds have emerged as important pathogens. Diagnosis of these rare fungi requires molecular techniques, and treatment data are limited. Herein, we present a case of with disseminated Rasamsonia infection involving the heart. Keywords: Chronic granulomatous disease, Filamentous fungi, Invasive fungal infections
Databáze: Directory of Open Access Journals