Studies of Sensitivity to Avian Flu Virus A/H5N1 in Chickens
| Autor: | A. A. Sergeev, O. V. P’Yankov, O. K. Demina, A. N. Shikov, Al. A. Sergeev, L. N. Shishkina, A. S. Safatov, A. P. Agafonov, A. N. Sergeev |
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| Jazyk: | ruština |
| Rok vydání: | 2012 |
| Předmět: |
вирус гриппа птиц а/h5n1
курица интраназальное заражение аэрозольное инфицирование оральное заражение интрагастральное инфицирование 50 % летальная доза накопление вируса органы и ткани курицы avian flu virus a/h5n1 chicken intranasal challenge aerosol challenge oral challenge intragastral challenge virus accumulation avian organs and tissues Infectious and parasitic diseases RC109-216 |
| Zdroj: | Проблемы особо опасных инфекций, Vol 0, Iss 3(113), Pp 71-73 (2012) |
| Druh dokumentu: | article |
| ISSN: | 0370-1069 2658-719X |
| DOI: | 10.21055/0370-1069-2012-3-71-73 |
| Popis: | appear to be highly virulent for chickens. The chance of AFV infection of chickens in case of intranasal challenge is 20 times as great as in the case of peroral one, and 300 times as great as in the case of intragastral one, which bears evidence to higher sensitivity to AFV of the tissues of avian respiratory organs, in comparison with the tissues of gastro-intestinal tract. Therewith, primary target organ for virus in intranasal infected birds is their respiratory channel (mucous membrane of the nasal cavity in particular). Registered is the possibility of existence of fecal-nasal AFV transfer mechanism in chickens. |
| Databáze: | Directory of Open Access Journals |
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