Effects of hormone replacement therapy on depressive and anxiety symptoms after oophorectomy

Autor: Danijela D. Ðoković, Jelena J. Jović, Jelena D. Ðoković, Marinela Ž. Knežević, Slavica Djukić-Dejanović, Dragana I. Ristić-Ignjatović
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Medicinski Glasnik, Vol 12, Iss 1, Pp 79-85 (2015)
Druh dokumentu: article
ISSN: 1840-0132
1840-2445
Popis: Aim To assess the effect of hormone replacement therapy on postoperative depression and anxiety symptoms. Methods In observational prospective study 80 women divided into two groups were evaluated: women who received estrogen and androgen replacement therapy after hysterectomy with bilateral oophorectomy before onset of menopause (35-45 years old) and a control group that consisted of perimenipausal women (45-55 years old). Hormone replacement therapy began one week after surgery. The severity of depression and anxiety was evaluated through the use of Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale. Subjects from the study group were interviewed right after the surgical treatment, one, two and three months later. Subjects from the control group were interviewed only once. Results The women who underwent surgery had a statistically significantly higher score in Hamilton Depression Scale (p
Databáze: Directory of Open Access Journals