SAPHO syndrome with a purely osteolytic form: A case report

Autor: Akira Kakiuchi, MD, Yayoi Yamamoto, MD, PhD, Akira Kanbe, MD, Daichi Kojima, MD, Ayako Hino, MD, PhD, Ayumi Horikawa, MD, PhD, Tsunehiro Doiuchi, MD, Hiroaki Kurihara, MD, PhD
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Radiology Case Reports, Vol 18, Iss 10, Pp 3612-3614 (2023)
Druh dokumentu: article
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2023.07.034
Popis: SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare, chronic autoinflammatory disorder that can present with a constellation of cutaneous and osteoarticular symptoms. Osteodestructive lesions are not pathognomonic, whereas hyperostosis and osteitis are the most prominent imaging findings. We report the case of a man with osteolytic changes of the lumbar vertebra and a history of palmoplantar pustulosis. Biopsy revealed no neoplasm, suggesting SAPHO syndrome. Our case demonstrates that knowledge of atypical radiologic findings is necessary for the diagnosis of SAPHO syndrome.
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