From Phosphorous to Arsenic: Changing the Classic Paradigm for the Structure of Biomolecules

Autor: Mark Brown, Pratima Agarwal, Ryan Knodle
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Biomolecules, Vol 2, Iss 2, Pp 282-287 (2012)
Druh dokumentu: article
ISSN: 2218-273X
DOI: 10.3390/biom2020282
Popis: Biomolecules are composed primarily of the elements carbon, nitrogen, hydrogen, oxygen, sulfur, and phosphorus. The structured assembly of these elements forms the basis for proteins, nucleic acids and lipids. However, the recent discovery of a new bacterium, strain GFAJ-1 of the Halomonadaceae, has shaken the classic paradigms for the architecture of life. Mounting evidence supports the claim that these bacteria substitute arsenic for phosphorus in macromolecules. Herein, we provide a brief commentary and fuel the debate related to what may be a most unusual organism.
Databáze: Directory of Open Access Journals