An investigation on the use of topical antibiotics for treating eczema and dermatitis in China

Autor: Juan Shao, Xin Wang, Zhongwen Zhang, Linfeng Li
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: European Journal of Inflammation, Vol 22 (2024)
Druh dokumentu: article
ISSN: 2058-7392
1721727X
DOI: 10.1177/1721727X241250289
Popis: Introduction: Bacterial infection secondary to eczema and dermatitis occurs frequently. However, due to the inconvenience of clinical bacterial culture procedure, clinical diagnosis of bacterial infection following eczema is typically based on the appearance of skin lesions. To date, no surveys on the use of topical antibiotics for treating eczema and dermatitis in China have been carried out. Methods: The present study investigated the factors influencing the use of topical antibiotics to treat eczema and dermatitis in China. Logistic regression model and chi-square test were employed to examine whether topical antibiotics cause contact irritation. Results: It was found that the proportion of patients with eczema and dermatitis who were previously treated with topical antibiotics was 72.40%. The patients’ residence regions (southern vs northern territories, p < .001), hospital levels (secondary-level and below vs third-level hospitals, p = .004), itching degrees (no itching, itching does not require scratching, itching requires scratching, and scratching affects sleep and life quality, p < .001), skin infection status (no obvious infection phenomenon, possible infection, and clear infection, p = .001), and skin lesion infection severity (mild, moderate, and severe, p < .001) all showed statistically significant differences in the univariate analysis of antibiotic ointment treatment factors. The percentage of patients experiencing contact irritation reactions resulting from the use of topical antibiotics was 2.60%. The incidence of exposure to irritation was higher in patients who used more than two types of topical antibiotics compared to patients treated with only one type of topical antibiotic (% vs %, chi-square test, p < .001). Conclusion: The number of individuals who used topical antibiotics for eczema and dermatitis was relatively high in China. The degree of itching, infection possibility, and degree of skin lesion infection were positively correlated with the patients’ previous topical antibiotic treatment.
Databáze: Directory of Open Access Journals
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