Autor: |
Ponkhi Doley, Srinivasamurthy Venkataramanappa, Panduranga Chikkannaiah |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Journal of the Scientific Society, Vol 47, Iss 3, Pp 180-184 (2020) |
Druh dokumentu: |
article |
ISSN: |
0974-5009 |
DOI: |
10.4103/jss.JSS_60_20 |
Popis: |
Introduction: Squamous cell carcinoma is the most common head and neck cancer. In spite of advances in the diagnosis and treatment, a prognosis still remains poor. Head-and Neck squamous cell carcinoma (HNSCC) is found to express human epidermal growth factor receptor 2 (Her 2) neu marker. Materials and Methods: The present study was conducted for a period of 1 year from January to December 2017. All the cases which have been pathologically diagnosed as HNSCC were included in the study. Results: During the study period, a total of 50 cases were observed. Male: female ratio was 1.7:1. In our study, buccal mucosa was the most common site (26'). Well-differentiated morphology was more common (36'), and 34' cases were positive for Her 2 Neu expression. Conclusion: Her 2 neu expression may not be a reliable molecular prognostic marker for HNSCC. |
Databáze: |
Directory of Open Access Journals |
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