Utility of Challenge Test in Immediate Hypersensitivity to Hydrocortisone Sodium Succinate
| Autor: | Adela Sisy Amaya-Mejía, Lucy Vania Galindo-Pacheco, Patricia María O’Farrill-Romanillos, Karen Alicia Rodríguez-Mireles, Freya Helena Campos-Romero, Leonel Gerardo Del Rivero-Hernández |
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| Jazyk: | English<br />Spanish; Castilian |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Revista Alergia México, Vol 61, Iss 1, Pp 32-37 (2014) |
| Druh dokumentu: | article |
| ISSN: | 0002-5151 2448-9190 |
| DOI: | 10.29262/ram.v61i1.19 |
| Popis: | Corticosteroid hypersensitivity is a complex phenomenon in which many factors interact, such as idiosyncrasy, intolerance or allergic reactions. The prevalence of immediate hypersensitivity reactions to corticosteroids is 0.2%-0.5%. Corticosteroids have major therapeutic implications; thus, when hypersensitivity is suspected, in-vitro and/or in-vivo testing can be performed to con rm diagnosis, being the drug challenge the gold standard. After de nitive diagnosis, cross-reactivity among the different corticosteroid groups should be considered, to choose wisely if corticosteroid therapy is still required. In Coopman classi cation, steroids belonging to groups A, B and D2 have high cross-reactivity, however, more studies are needed to determine the degree of cross-reaction among these drugs. This paper presents the case of a woman, in who hypersensitivity to hydrocortisone succinate was con rmed by drug challenge test. |
| Databáze: | Directory of Open Access Journals |
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