Trends and health burden of hospitalized acute respiratory infections and impact of Haemophilus influenza immunization in a Tunisian university hospital: a twelve-year study

Autor: Manel Ben Fredj, Wafa Dhouib, Meriem Kacem, Cyrine Bennasrallah, Ons Mehrez, Hela Abroug, Imen Zemni, Aicha Gardabou, Koubaa Jamel, Slaheddine Chouchene, Naceur Rouatbi, Asma Belguith Sriha
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Libyan Journal of Medicine, Vol 15, Iss 1 (2020)
Druh dokumentu: article
ISSN: 1993-2820
1819-6357
19932820
DOI: 10.1080/19932820.2020.1783048
Popis: Background We aimed to describe the episodes and trends of admissions for community-acquired Respiratory Infections (RI) over a 12-year period and to assess the impact of Haemophilus influenza type b (Hib) vaccine on RI admissions in children aged up to 3 years. Methods We conducted a twelve-year retrospective observational study on all community-acquired RI admitted to Fattouma Bourguiba Hospital in Monastir Governorate (Tunisia) from 1 January 2002 to 31 December 2013. RI cases were selected from the Regional Registry of Hospital Morbidity. Data were coded according to ICD-10. To assess the impact of the Hib vaccine, three cohorts were defined based on vaccine status (unvaccinated cohort, first vaccinated cohort (VC) by monovalent form and second VC by pentavalent combination). Results Admissions for RI represented 17.6% (CI95%: 17.3–18.1) of all communicable diseases hospitalizations (n = 6 061/34 289). The crude incidence rates (CIR) per 100,000 inh were 24.2 for upper RI (URI) and 77.5 and for Lower RI (LRI) (p
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