Regulation of Apoptosis in African Swine Fever Virus–Infected Macrophages

Autor: Laslo Zsak, John G. Neilan
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Zdroj: The Scientific World Journal, Vol 2, Pp 1186-1195 (2002)
Druh dokumentu: article
ISSN: 1537-744X
DOI: 10.1100/tsw.2002.214
Popis: A number of viruses have evolved antiapoptotic mechanisms to promote infected-cell survival, either to ensure efficient productive viral replication or to promote long-term survival of virus-infected cells. Recent studies identified critical African swine fever virus genes involved in the complex regulation of ASFV-host interactions. Here we review the present knowledge of the recently identified ASFV genes with special attention to those which affect viral virulence, host range, and pathogenesis by regulating viral-induced apoptotic mechanisms.
Databáze: Directory of Open Access Journals