Effectiveness of combined antyviral therapy in children with chronic hepatitis C

Autor: G. P. Martynova, I. A. Solovyova, T. A. Zhukovskaya, A. B. Belkina, Ya. A. Bogvilene, I. A. Kutishcheva, S. V. Evreimova
Jazyk: ruština
Rok vydání: 2014
Předmět:
Zdroj: Журнал инфектологии, Vol 5, Iss 2, Pp 37-42 (2014)
Druh dokumentu: article
ISSN: 2072-6732
DOI: 10.22625/2072-6732-2013-5-2-37-42
Popis: The paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic viral hepatitis C aged from 3 to 17, who underwent regular medical check-ups in City Clinical Hospital № 20 named after I.S. Berzon in Krasnoyarsk. Evaluation of effectiveness of combined antiviral therapy revealed that patients with genotype 1 had an immediate virologic response in 78,5% of cases, 83,3% of patients with genotype 2, 3 had a stable virologic response.
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