Bergenin, Suatu Dihidroisokumarin dari Kayu dan Kulit Batang Shorea Stenoptera Burck§

Autor: Euis Holisotan Hakim, Rudiyansyah Rudiyansyah, Iqbal Musthapa, Koichi Takeya
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Journal of Mathematical and Fundamental Sciences, Vol 35, Iss 2 (2013)
Druh dokumentu: article
ISSN: 2337-5760
2338-5510
DOI: 10.5614/itbj.sci.2003.35.2.1
Popis: Bergenin, a dihydroisocoumarin derivative of glucopyranosyl gallic acid had been isolated for the first time from ethyl acetate extracts of the heartwood and tree bark, together with (-)-α-viniferin from the tree bark of Shorea stenoptera. The structure of bergenin was elucidated based on analysis of spectroscopic data UV, IR, MS, 1H and 13C NMR. Bergenin showed weak cytotoxic activity against murine leukemia P-388 cells (IC50 >100 μg/mL), and also weak toxicity against Artemia salina shrimps (LC50 >500 μg/mL).
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