Arterial hypertension and brain damage. New targets of therapy

Autor:	S N Yanishevskiy, D A Mirnaya, R V Andreyev
Jazyk:	ruština
Rok vydání:	2014
Předmět:	arterial hypertension brain’s perfusion disorders mild cognitive impairment olmesartan medoxomil Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Системные гипертензии, Vol 11, Iss 4, Pp 68-70 (2014)
Druh dokumentu:	article
ISSN:	2075-082X 2542-2189
Popis:	Objective: to assess the feasibility of ARBs to reduce hypoperfusion of the brain that develops in patients with arterial hypertension of 1-2 degrees. Material and methods. A study of changes in the ultrasonic Doppler index (RI resistivity index and pulsatility index PI) and the structure of neurological symptoms in patients with arterial hypertension of 1-2 degrees (n=86) due to 53-week olmesartan medoxomil reception (Cardosal®). Results. Patients with arterial hypertension of 1-2 degrees have diagnosed diffuse neurological symptoms and mild cognitive impairment. Doppler ultrasound revealed an increase in peripheral resistance index in the internal carotid and middle cerebral arteries, compared with patients without hypertension. Through 53 weeks therapy of olmesartan medoxomil (Cardosal®) observed a statistically significant decrease in peripheral vascular resistance (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/37323b9451114bdba159f0b9985f4836 Zobrazit plný text záznamu View record in DOAJ