Takotsubo Syndrome Associated with Neurally Mediated Reflex Syncope: A Meta-summary of Case Reports and Literature Review

Autor: Vincenzo Russo, Filippo Pecori, Nicola Colalillo, Nicola Massimo, Giovanni Battista Valentino, Angelo Comune, Erika Parente, Gerardo Nigro
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Reviews in Cardiovascular Medicine, Vol 25, Iss 7, p 264 (2024)
Druh dokumentu: article
ISSN: 1530-6550
DOI: 10.31083/j.rcm2507264
Popis: Background: Neurally mediated reflex syncope (NMRS) has been recently described as a possible trigger of Takotsubo syndrome (TTS). There are few data in the literature about this association. Methods: In the present meta-summary, 6 case reports describing patients who experienced TTS following an NMRS episode were included. Patient characteristics, triggers and type of syncope were collected. Results: A total of 7 patients with a median age of 63.4 years (interquartile range, IQR: 47.5–76) were evaluated; 71.4% were females, mainly in the menopausal state (80%). The TTS triggers were: vasovagal syncope in 6 patients (85.7%) and situational syncope in 1 patient (14.3%). 2 patients underwent a comprehensive clinical evaluation which showed a cardioinhibitory response. Conclusions: NMRS due to sudden orthostatism and emotional stress, mainly with a cardioinhibitory response, has been associated with the onset of TTS, in particular among female patients in a menopausal state.
Databáze: Directory of Open Access Journals