Whole blood DNA methylation analysis reveals respiratory environmental traits involved in COVID-19 severity following SARS-CoV-2 infection

Autor: Guillermo Barturen, Elena Carnero-Montoro, Manuel Martínez-Bueno, Silvia Rojo-Rello, Beatriz Sobrino, Óscar Porras-Perales, Clara Alcántara-Domínguez, David Bernardo, Marta E. Alarcón-Riquelme
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-32357-2
Popis: Genetic associations with severe COVID-19 have been discovered, but epigenetic associations are not as well described. Here, the authors perform a genome-wide epigenetic analysis of COVID-19 patients, discovering an interaction between environmental exposure, genetics, and epigenetics which might play a role in severe disease.
Databáze: Directory of Open Access Journals
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