Effects of Omega-3-Rich Pork Lard on Serum Lipid Profile and Gut Microbiome in C57BL/6NJ Mice

Autor: Anantawat Koontanatechanon, Manoosak Wongphatcharachai, Nutthawan Nonthabenjawan, Pichaya Jariyahatthakij, Thanchanok Khorporn, Wanpeuch Parnsen, Benjawan Keattisin, Pattarin Leksrisompong, Pairat Srichana, Sattrachai Prasopdee, Sittiruk Roytrakul, Kusuma Sriyakul, Veerachai Thitapakorn, Kammal Kumar Pawa
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Food Science, Vol 2022 (2022)
Druh dokumentu: article
ISSN: 2314-5765
DOI: 10.1155/2022/9269968
Popis: Background and Aims. Hyperlipidemia is a risk factor for cardiovascular diseases. This study is aimed at investigating the effects of consuming omega-3-rich pork lard on the serum lipid profile and gut microbiome of the mice model. Methods and Results. We divided 23 C57BL/6NJ males (16-week-old) into 3 groups, and each group received either a control diet, a high-fat diet of coconut oil (coconut oil), or a high-fat diet of omega-3-rich pork lard (omega lard) for 28 days. Thereafter, fasting serum lipids and fecal microbiomes were analyzed. The serum cholesterol, triglyceride, and LDL levels of the omega lard-treated group were significantly reduced compared to the coconut oil-treated group (P
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