| Autor: |
Adam Wolf, Faria Khimani, Braian Yoon, Coltin Gerhart, Dakota Endsley, Anish K. Ray, Angelito F. Yango, Stuart D. Flynn, Gregory Y.H. Lip, Stevan A. Gonzalez, Mohanakrishnan Sathyamoorthy |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Thrombosis Update, Vol 8, Iss , Pp 100110- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2666-5727 |
| DOI: |
10.1016/j.tru.2022.100110 |
| Popis: |
It is now well established that infection with SARS-CoV-2 resulting in COVID-19 disease includes a severely symptomatic subset of patients in whom an aggressive and/or dysregulated host immune response leads to cytokine storm syndrome (CSS) that may be further complicated by thrombotic events, contributing to the severe morbidity and mortality observed in COVID-19. This review provides a brief overview of cytokine storm in COVID-19, and then presents a mechanistic discussion of how cytokine storm affects integrated pathways in thrombosis involving the endothelium, platelets, the coagulation cascade, eicosanoids, auto-antibody mediated thrombosis, and the fibrinolytic system. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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